Description

3β-Acetylamino-5α-Cholestane is a high-purity steroidal derivative, specifically a cholestane-based compound modified with an acetylamino group at the 3-beta position. This specific molecular architecture makes it a valuable intermediate and reference standard for advanced pharmaceutical research and synthesis. It is primarily utilized by R&D chemists and process development scientists working in the life sciences sector. The compound's defined structure is critical for studies in steroid chemistry, metabolic pathway analysis, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroidal drugs and bioactive molecules.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of steroidal compounds via HPLC, GC-MS, or NMR.
• Biochemical Research: Serves as a precursor or model compound in studies investigating cholesterol metabolism, membrane biology, and hormone signaling pathways.
• Process Chemistry: Employed in scaling up and optimizing synthetic routes for steroidal active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic and medicinal chemistry.

Basic Information

Product Name	3β-Acetylamino-5α-Cholestane
CAS No.	1912-64-7
Molecular Formula	C₂₉H₅₁NO
Molecular Weight	429.73 g/mol
Synonyms	3β-Acetamido-5α-cholestane; 5α-Cholestan-3β-ylacetamide; 3β-Acetylamino-5α-cholestane; Cholestane-3β-acetamide, 5α-; 3β-Acetamido-5α-cholestane; NSC 69187; (3β)-3-(Acetylamino)-5α-cholestane
EINECS	217-636-7

Quality Control

Our 3β-Acetylamino-5α-Cholestane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.