Description

2-Chloro-4-(Pyrrolidin-1-Yl)Quinazoline is a high-value, functionalized quinazoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel pharmacologically active compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors and other biologically active quinazoline-based compounds for therapeutic research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides that leverage the quinazoline pharmacophore.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular probes to study enzyme function and cellular pathways.
• Material Science: Investigated as a monomer or precursor for the synthesis of specialty polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical spaces.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) engaged in the custom synthesis of complex organic molecules for clients.

Basic Information

Product Name	2-Chloro-4-(Pyrrolidin-1-Yl)Quinazoline
CAS No.	1804-50-8
Molecular Formula	C₁₂H₁₂ClN₃
Molecular Weight	233.70 g/mol
Synonyms	2-Chloro-4-(1-pyrrolidinyl)quinazoline; 4-(Pyrrolidin-1-yl)-2-chloroquinazoline; 2-Chloro-4-pyrrolidin-1-ylquinazoline; Quinazoline, 2-chloro-4-(1-pyrrolidinyl)-; 1804-50-8; 2-Chloro-4-(N-pyrrolidinyl)quinazoline; 2-Chloro-4-pyrrolidinoquinazoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Pyrrolidin-1-Yl)Quinazoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. For custom synthesis projects, we can tailor specifications to meet specific project requirements, including compliance with GMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.