Description

Deoxysepiapterin is a key intermediate in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for nitric oxide synthases and aromatic amino acid hydroxylases. This compound matters for its critical role in biochemical research focused on metabolic pathways, enzyme function, and the study of related disorders. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers working on neurotransmitter synthesis, cellular metabolism, and potential therapeutic applications.

Application

• Biochemical Research: Used as a vital precursor in studies of the tetrahydrobiopterin (BH4) biosynthesis and regeneration pathways.
• Enzyme Activity Studies: Serves as a substrate or intermediate for investigating the kinetics and mechanisms of enzymes like sepiapterin reductase.
• Pharmaceutical Development: Employed in the research and development of potential therapeutics targeting BH4-deficient conditions, such as certain forms of phenylketonuria (PKU) and cardiovascular diseases.
• Diagnostic Reagent Manufacturing: Utilized in the formulation of diagnostic kits and assays for measuring biopterin levels or related enzyme activities in clinical samples.
• Cell Culture & Metabolism Research: Applied in cell-based studies to modulate intracellular BH4 levels and observe effects on nitric oxide production and amino acid metabolism.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical and research laboratories.

Basic Information

Product Name	Deoxysepiapterin
CAS No.	1797-87-1
Molecular Formula	C9H11N5O3
Molecular Weight	237.22 g/mol
Synonyms	6-(1,2-Dihydroxypropyl)-7,8-dihydropterin; 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one; 6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydropterin; D-DS; Deoxysepiapterin; 6-(1,2-Dihydroxypropyl)-7,8-dihydropterin; 6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydropterin
EINECS	Contact for details

Quality Control

Our Deoxysepiapterin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC for assay and purity, and is suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.