Description

8,8'-Ethylenebis[3,7-Dihydro-1,3-Dimethyl-2-Thioxo-1H-Purin-6(2H)-One] is a specialized purine derivative with a unique bridged dimeric structure, serving as a critical intermediate in advanced organic synthesis. This compound matters for its role in the development of novel pharmaceutical agents, particularly in the research of adenosine receptor modulators and xanthine-based therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel adenosine receptor antagonists and xanthine derivatives with potential therapeutic applications.
• Biochemical Research: Used as a reference standard or probe in enzymatic studies related to purine metabolism and signal transduction pathways.
• Agrochemical Development: Serves as a precursor in the synthesis of new plant growth regulators or pesticides with purine-like activity.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex heterocyclic frameworks for material science or catalyst development.
• Academic Research: Utilized in universities and research institutes for investigating structure-activity relationships (SAR) of dimeric purine compounds.

Basic Information

Product Name	8,8'-Ethylenebis[3,7-Dihydro-1,3-Dimethyl-2-Thioxo-1H-Purin-6(2H)-One]
CAS No.	1784-50-5
Molecular Formula	C₁₈H₂₀N₁₀O₂S₂
Molecular Weight	472.56 g/mol
Synonyms	1,3-Dimethyl-8,8'-ethylenebis(3,7-dihydro-1,3-dimethyl-2-thioxo-1H-purin-6(2H)-one); Ethylenebis(theophylline-8-thione); 8,8'-Ethylenebis(1,3-dimethyl-2-thioxoxanthine); 1,3-Dimethyl-8,8'-ethylenebis(2-thioxoxanthine); Theophylline-8-thione ethylene dimer; NSC 82196; Bis(1,3-dimethyl-2-thioxo-2,3-dihydro-1H-purin-6(7H)-one) ethylene bridge
EINECS	217-234-5

Quality Control

Our 8,8'-Ethylenebis[3,7-Dihydro-1,3-Dimethyl-2-Thioxo-1H-Purin-6(2H)-One] is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, the container should be kept sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.