Description

2,4,5,6-Tetrachloropyrimidine is a versatile halogenated heterocyclic building block essential for advanced organic synthesis. Its high reactivity, particularly at the 4 and 6 positions, makes it a critical intermediate for constructing complex molecules in high-value industries. This compound is primarily sought after by R&D chemists and process developers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to manufacture herbicides, fungicides, and insecticides, where the pyrimidine core provides essential bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands for transition metal catalysis.
• Material Science: Building block for organic electronic materials, such as electron-transport layers and components for OLEDs.
• Custom Synthesis & R&D: Employed in research laboratories for method development and the creation of novel chemical entities.
• Dye and Pigment Intermediate: Used in the synthesis of specialized colorants and photographic chemicals.

Basic Information

Product Name	2,4,5,6-Tetrachloropyrimidine
CAS No.	1780-40-1
Molecular Formula	C4Cl4N2
Molecular Weight	215.87 g/mol
Synonyms	Pyrimidine, 2,4,5,6-tetrachloro-; Tetrachloropyrimidine; 2,4,5,6-Tetrachloro-1,3-diazine; NSC 402124; s-Tetrachloropyrimidine; 1,3-Diazine, 2,4,5,6-tetrachloro-
EINECS	217-218-5

Quality Control

Our 2,4,5,6-Tetrachloropyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	148 - 152 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.