Description

5-(Bromomethyl)-4,6-Dichloro-2-(Chloromethyl)Pyrimidine is a versatile and highly functionalized halogenated pyrimidine building block, essential for advanced organic synthesis. Its multi-reactive sites make it a critical intermediate for constructing complex molecular architectures with high precision and efficiency. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides due to its reactive halogen substituents.
• Material Science Research: Serves as a building block for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), and specialty chemicals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings to introduce the pyrimidine core into more complex systems.
• Nucleic Acid Chemistry: Employed in the modification of nucleosides and nucleotides for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, multi-functional heterocyclic compounds.

Basic Information

Product Name	5-(Bromomethyl)-4,6-Dichloro-2-(Chloromethyl)Pyrimidine
CAS No.	1780-35-4
Molecular Formula	C6H4BrCl3N2
Molecular Weight	290.37 g/mol
Synonyms	2-(Chloromethyl)-5-(bromomethyl)-4,6-dichloropyrimidine; 4,6-Dichloro-2-(chloromethyl)-5-(bromomethyl)pyrimidine; 5-Bromomethyl-4,6-dichloro-2-chloromethylpyrimidine; Pyrimidine, 5-(bromomethyl)-4,6-dichloro-2-(chloromethyl)-
EINECS	217-218-3

Quality Control

Our 5-(Bromomethyl)-4,6-Dichloro-2-(Chloromethyl)Pyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.