Description

4,6-Dichloro-2,5-Dimethyl Pyrimidine is a versatile halogenated pyrimidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic reactivity of its chlorine atoms, enabling precise functionalization to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and kinase inhibitor drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its pyrimidine core.
• Organic Synthesis Reagent: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the pyrimidine moiety.
• Material Science Research: Employed in the development of organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Utilized as a scaffold for creating molecular probes and inhibitors to study biological pathways and enzyme functions.

Basic Information

Product Name	4,6-Dichloro-2,5-Dimethyl Pyrimidine
CAS No.	1780-33-2
Molecular Formula	C6H6Cl2N2
Molecular Weight	177.03 g/mol
Synonyms	2,5-Dimethyl-4,6-dichloropyrimidine; 4,6-Dichloro-2,5-dimethylpyrimidine; 2,5-Dimethyl-4,6-dichloro-1,3-diazine; NSC 403697; Pyrimidine, 4,6-dichloro-2,5-dimethyl-; 4,6-Dichloro-2,5-dimethyl-1,3-diazine
EINECS	217-217-5

Quality Control

Our 4,6-Dichloro-2,5-Dimethyl Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.