Description

4,5,6-Trichloro-2-Methylpyrimidine is a halogenated pyrimidine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in its reactive chlorinated sites, which allow for selective functionalization to create complex molecular architectures. This intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its pyrimidine core.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of complex heterocyclic dyes and colorants.

Basic Information

Product Name	4,5,6-Trichloro-2-Methylpyrimidine
CAS No.	1780-28-5
Molecular Formula	C5H3Cl3N2
Molecular Weight	197.45 g/mol
Synonyms	2-Methyl-4,5,6-trichloropyrimidine; 4,5,6-Trichloro-2-methylpyrimidine; 2-Methyl-4,5,6-trichloro-1,3-diazine; NSC 403697; Trichloromethylpyrimidine; Pyrimidine, 4,5,6-trichloro-2-methyl-
EINECS	217-219-6

Quality Control

Our 4,5,6-Trichloro-2-Methylpyrimidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended long-term storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.