Description

4,5,6-Trichloropyrimidine CAS NO 1780-27-4 is a versatile halogenated heterocyclic building block essential for advanced organic synthesis. Its value lies in the reactivity of its chlorine atoms, enabling selective substitution to create complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Ligand and Catalyst Development: Employed to create novel pyrimidine-based ligands for metal complexes used in catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4,5,6-Trichloropyrimidine
CAS No.	1780-27-4
Molecular Formula	C4HCl3N2
Molecular Weight	183.42 g/mol
Synonyms	4,5,6-Trichloro-1,3-diazine; Pyrimidine, 4,5,6-trichloro-; s-Triazine, 2,4,6-trichloro- (related isomer); Trichloropyrimidine; NSC 403697; AI3-28445; CCRIS 5986
EINECS	217-219-5

Quality Control

Our 4,5,6-Trichloropyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.