Description

5-Pyrimidinecarbonitrile, 1,2-Dihydro-2-Oxo- (7Ci,9Ci) is a high-purity heterocyclic nitrile building block of significant interest in advanced organic synthesis. This compound serves as a critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, material science, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs, kinase inhibitors, and other heterocyclic drug candidates.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators with pyrimidine-based cores.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzymatic activity and biological pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialty chemicals and complex organic molecules.

Basic Information

Product Name	5-Pyrimidinecarbonitrile, 1,2-Dihydro-2-Oxo- (7Ci,9Ci)
CAS No.	1753-49-7
Molecular Formula	C5H3N3O
Molecular Weight	121.10 g/mol
Synonyms	2-Oxo-1,2-dihydropyrimidine-5-carbonitrile; 5-Cyanouracil; 5-Cyano-2-hydroxypyrimidine; 5-Cyano-1H-pyrimidin-2-one; Uracil-5-carbonitrile; 2-Hydroxy-5-cyanopyrimidine; 1H-Pyrimidine-5-carbonitrile, 2-hydroxy-; 1753-49-7
EINECS	217-149-5

Quality Control

Our 5-Pyrimidinecarbonitrile, 1,2-Dihydro-2-Oxo- (7Ci,9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.