Description

5-Fluorobiphenyl-2-Amine is a high-purity fluorinated aromatic amine building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of pharmaceuticals, agrochemicals, and functional materials. It is particularly valuable for researchers and manufacturers in the pharmaceutical and specialty chemical industries seeking to introduce fluorine atoms into complex molecular architectures to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances bioactivity, stability, and environmental persistence.
• Material Science Precursor: Employed in the creation of specialty polymers, liquid crystals, and organic light-emitting diodes (OLEDs) due to its rigid biphenyl structure and fluorine substitution.
• Chemical Research & Development: Serves as a versatile building block in academic and industrial R&D for constructing complex fluorinated heterocycles and functionalized biphenyl derivatives.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized fluorinated dyes and colorants with unique spectral properties.

Basic Information

Product Name	5-Fluorobiphenyl-2-Amine
CAS No.	1717-22-2
Molecular Formula	C₁₂H₁₀FN
Molecular Weight	187.21 g/mol
Synonyms	2-Amino-5-fluorobiphenyl; (5-Fluoro-2-biphenylyl)amine; 5-Fluoro-2-biphenylamine; 2-Biphenylamine, 5-fluoro-; 5-Fluoro[1,1'-biphenyl]-2-amine; 2-Amino-5-phenylfluorobenzene; 5-Fluoro-2-aminobiphenyl
EINECS	Contact for details

Quality Control

Our 5-Fluorobiphenyl-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your specific research or production requirements. Custom purity grades, including pharmaceutical intermediates grade, are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0% (Standard Grade)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.