Description

2-Pyrimidinamine, 5-Fluoro- (9Ci) is a high-purity fluorinated pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with tailored biological and material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of fluorinated nucleoside analogs, kinase inhibitors, and other active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom's ability to modulate bioactivity and stability.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: A versatile reagent for introducing the 5-fluoropyrimidine moiety into more complex molecular architectures via cross-coupling, substitution, and other organic reactions.
• Biochemical Research: Employed in the study of enzyme mechanisms and as a probe in metabolic pathway analysis due to its structural similarity to natural pyrimidines.

Basic Information

Product Name	2-Pyrimidinamine, 5-Fluoro- (9Ci)
CAS No.	1683-85-8
Molecular Formula	C4H4FN3
Molecular Weight	113.09 g/mol
Synonyms	5-Fluoropyrimidin-2-amine; 2-Amino-5-fluoropyrimidine; 5-Fluoro-2-pyrimidinamine; 5-Fluoropyrimidine-2-amine; 5-Fluoro-2-aminopyrimidine; 2-Pyrimidinamine, 5-fluoro-; 5-Fluoro-2-pyrimidinylamine
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinamine, 5-Fluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.