Description

Pyrimidine, 2-Amino-4-Chloro-5-Fluoro- (7Ci,8Ci) is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its precise molecular structure, which enables the introduction of specific functional groups essential for developing active pharmaceutical ingredients and agrochemicals. It is primarily required by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of novel compounds and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated and chlorinated active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the halogenated pyrimidine core contributes to biological activity.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new molecular entities.
• Material Science: Potential intermediate in the synthesis of specialty polymers and organic electronic materials requiring specific heterocyclic structures.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and verification in pharmaceutical analysis.

Basic Information

Product Name	Pyrimidine, 2-Amino-4-Chloro-5-Fluoro- (7Ci,8Ci)
CAS No.	1683-75-6
Molecular Formula	C4H3ClFN3
Molecular Weight	147.54 g/mol
Synonyms	2-Amino-4-chloro-5-fluoropyrimidine; 5-Fluoro-4-chloropyrimidin-2-amine; 4-Chloro-5-fluoro-2-pyrimidinamine; 2-Pyrimidinamine, 4-chloro-5-fluoro-; 4-Chloro-5-fluoropyrimidin-2-ylamine; 1683-75-6; 5-Fluoro-4-chloro-2-aminopyrimidine; 4-Chloro-5-fluoro-2-aminopyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-Amino-4-Chloro-5-Fluoro- (7Ci,8Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.