Description

2-Chloropurine is a versatile halogenated purine derivative that serves as a critical synthetic intermediate in organic and medicinal chemistry. Its primary value lies in its reactivity, where the chlorine atom at the 2-position can be readily displaced by various nucleophiles, enabling the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of nucleoside analogs, antiviral agents, and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs and antiviral drugs, including potential candidates for cancer and viral infection therapies.
• Agrochemical Research: Used in developing novel herbicides and plant growth regulators by modifying the purine scaffold.
• Biochemical Tool Compound: Serves as a precursor for labeled compounds and probes used in metabolic pathway studies and enzymatic research.
• Organic Synthesis: A versatile reagent for constructing fused pyrimidine and imidazole ring systems through cross-coupling and substitution reactions.
• Academic & R&D: Fundamental starting material in university and contract research organization (CRO) laboratories for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	2-Chloropurine
CAS No.	1681-15-8
Molecular Formula	C5H3ClN4
Molecular Weight	154.56 g/mol
Synonyms	2-Chloro-1H-purine; 2-Chloro-9H-purine; 2-Chloropurine; Purine, 2-chloro-; 2-Chloro-7H-purine; 2-Chloro-3H-purine; 6-Amino-2-chloropurine (tautomer); NSC 74845
EINECS	Contact for details

Quality Control

Our 2-Chloropurine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.