Description

n-(2,4-Dinitrophenyl)-L-Phenylalanine is a specialized derivative of the amino acid L-phenylalanine, featuring a 2,4-dinitrophenyl (DNP) protecting group. This compound is of significant value in peptide synthesis and biochemical research, where it serves as a key intermediate for the selective modification and analysis of peptide structures. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in advanced organic synthesis and proteomics.

Application

• Peptide Synthesis Intermediate: Acts as a key building block in solid-phase and solution-phase peptide synthesis, where the DNP group serves as a protective moiety.
• Biochemical Research Reagent: Used in studies of enzyme kinetics, protein labeling, and the development of analytical methods for amino acid detection.
• Pharmaceutical Development: Employed in the research and synthesis of novel peptide-based drug candidates and therapeutic agents.
• Chromatography Reference Standard: Serves as a high-purity standard for calibration in HPLC and other analytical techniques within quality control laboratories.
• Proteomics and Bioconjugation: Utilized in the site-specific modification of proteins and peptides for diagnostic or research purposes.

Basic Information

Product Name	n-(2,4-Dinitrophenyl)-L-Phenylalanine
CAS No.	1655-54-5
Molecular Formula	C15H13N3O6
Molecular Weight	331.28 g/mol
Synonyms	N-(2,4-Dinitrophenyl)-L-phenylalanine; L-Phenylalanine, N-(2,4-dinitrophenyl)-; DNP-L-Phenylalanine; 2,4-Dinitrophenyl-L-phenylalanine; (S)-2-((2,4-Dinitrophenyl)amino)-3-phenylpropanoic acid; N-2,4-DNP-L-Phe; N-DNP-L-Phenylalanine; N-(2,4-DNP)-Phe-OH
EINECS	Contact for details

Quality Control

Our n-(2,4-Dinitrophenyl)-L-Phenylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.