Description

Melperone Hydrochloride is a high-purity pharmaceutical active ingredient (API) belonging to the butyrophenone class of compounds. It is a critical intermediate and reference standard in the research and development of neuroleptic and antipsychotic medications. This compound is essential for pharmaceutical manufacturers, analytical laboratories, and research institutions focused on central nervous system (CNS) therapeutics and quality control.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active pharmaceutical substance in the formulation of neuroleptic medications.
• Reference Standard: Serves as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in pharmaceutical analysis.
• Biochemical Research: Used in neuroscience and pharmacological studies to investigate dopamine receptor antagonism and its effects on the central nervous system.
• Analytical Testing: Employed as a standard in High-Performance Liquid Chromatography (HPLC), Mass Spectrometry (MS), and other analytical techniques for purity assessment and identification.
• Process Development: Acts as a key intermediate in the synthesis and scale-up processes for advanced pharmaceutical manufacturing.

Basic Information

Product Name	Melperone Hydrochloride
CAS No.	1622-79-3
Molecular Formula	C21H27FNO2 • HCl
Molecular Weight	395.90 g/mol
Synonyms	1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone Hydrochloride; Methylperone Hydrochloride; Buronil; 4'-Fluoro-4-(4-methyl-1-piperidinyl)butyrophenone Hydrochloride; FG 5111; CAS 1622-79-3
EINECS	Contact for details

Quality Control

Our Melperone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and absence of critical impurities. We adhere to relevant industry guidelines to support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.