Description

8-Chloro-7-(2-Chlorobenzyl)-1,3-Dimethyl-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, synthetically derived xanthine derivative with a unique chlorobenzyl substitution. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis, valued for its defined molecular architecture. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential adenosine receptor antagonists and other biologically active purine-based compounds.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities targeting neurological and cardiovascular pathways.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic molecules in custom synthesis and process development.
• Biochemical Research: Potential tool compound for investigating enzyme inhibition and signal transduction mechanisms related to purinergic systems.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	8-Chloro-7-(2-Chlorobenzyl)-1,3-Dimethyl-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	1604-77-9
Molecular Formula	C₁₄H₁₂Cl₂N₄O₂
Molecular Weight	339.18 g/mol
Synonyms	8-Chloro-7-(2-chlorobenzyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 8-Chloro-7-(2-chlorobenzyl)theophylline; 1,3-Dimethyl-8-chloro-7-(2-chlorobenzyl)xanthine; 8-Chloro-7-(o-chlorobenzyl)-1,3-dimethylxanthine; 1604-77-9; 8-Chloro-7-(2-chlorobenzyl)theophylline; 7-(2-Chlorobenzyl)-8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our production of 8-Chloro-7-(2-Chlorobenzyl)-1,3-Dimethyl-3,7-Dihydro-1H-Purine-2,6-Dione adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting research and pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.