Description

Nalpha-(2,4-Dinitrophenyl)-L-Arginine is a chemically modified derivative of the essential amino acid L-arginine, featuring a 2,4-dinitrophenyl (DNP) protecting group on its α-amino function. This compound is a critical intermediate and reagent in peptide synthesis and biochemical research, valued for its role in introducing specific functional handles or in analytical derivatization techniques. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in proteomics, method development, and the production of specialized peptides.

Application

• Peptide Synthesis Intermediate: Serves as a key building block in solid-phase and solution-phase peptide synthesis, where the DNP group acts as a temporary protecting group for the α-amino function of arginine.
• Biochemical Research Reagent: Used in enzymatic studies and protein chemistry research to investigate arginine-specific modifications or as a substrate analog.
• Proteomics and Labeling Studies: Can be utilized in mass spectrometry-based proteomic workflows for selective labeling or enrichment strategies targeting arginine residues.
• Pharmaceutical Development: Acts as a specialized intermediate in the research and development of novel peptide-based therapeutics and diagnostic agents.

Basic Information

Item	Details
Product Name	Nalpha-(2,4-Dinitrophenyl)-L-Arginine
CAS No.	1602-42-2
Molecular Formula	C12H17N7O6
Molecular Weight	355.31 g/mol
Synonyms	Nα-(2,4-Dinitrophenyl)-L-arginine; DNP-Arg; Nα-DNP-L-arginine; L-Arginine, N-[2,4-dinitrophenyl]-; (S)-2-Amino-5-guanidinopentanoic acid N-(2,4-dinitrophenyl) derivative; 2,4-Dinitrophenyl-L-arginine; N-(2,4-Dinitrophenyl)arginine
EINECS	Contact for details

Quality Control

Our Nalpha-(2,4-Dinitrophenyl)-L-Arginine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and specific tests for residual solvents and moisture content. We ensure compliance with relevant industry standards for research chemicals. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.