Description

Benzenamine, 4-(2-Fluoroethoxy)- is a fluorinated aniline derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring a fluoroethoxy side chain, makes it a valuable intermediate for creating compounds with enhanced biological activity and specific physicochemical properties. This chemical is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system or requiring fluorinated motifs for metabolic stability.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides, where the fluorine atom can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Used in the development of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs) to modify charge transport and emission properties.
• Polymer & Resin Modification: Acts as a monomer or curing agent in specialty polymer formulations to introduce fluorine-based characteristics like chemical resistance or low surface energy.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the aniline and fluoroethoxy groups contribute to color fastness and unique spectral properties.
• Cross-coupling Reactions: Functions as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	Benzenamine, 4-(2-Fluoroethoxy)-
CAS No.	1547-12-2
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	4-(2-Fluoroethoxy)aniline; 1-Fluoro-2-(4-aminophenoxy)ethane; p-(2-Fluoroethoxy)aniline; 4-Aminophenyl 2-fluoroethyl ether; 2-Fluoroethyl 4-aminophenyl ether; 4-(β-Fluoroethoxy)aniline; 2-(4-Aminophenoxy)ethyl fluoride; Aniline, p-(2-fluoroethoxy)-
EINECS	Contact for details

Quality Control

Every batch of Benzenamine, 4-(2-Fluoroethoxy)- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.