Description

4-Hydroxy-6-(Trifluoromethyl)Pyrimidine is a high-value fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a hydroxyl group and a trifluoromethyl substituent, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides where the trifluoromethyl group can improve efficacy and environmental stability.
• Material Science Research: Employed as a monomer or functional additive in the creation of specialty polymers and advanced organic materials.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for metal complexes and catalysts used in asymmetric synthesis.

Basic Information

Product Name	4-Hydroxy-6-(Trifluoromethyl)Pyrimidine
CAS No.	1546-78-7
Molecular Formula	C5H3F3N2O
Molecular Weight	164.09 g/mol
Synonyms	6-(Trifluoromethyl)-4-pyrimidinol; 4-Pyrimidinol, 6-(trifluoromethyl)-; 4-Hydroxy-6-trifluoromethylpyrimidine; 6-Trifluoromethyl-4-hydroxypyrimidine; 4-Hydroxy-6-(trifluoromethyl)pyrimidine; 4(1H)-Pyrimidinone, 6-(trifluoromethyl)-; 6-Trifluoromethylpyrimidin-4-ol
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-6-(Trifluoromethyl)Pyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.