Description

3,5-Difluoro-4-Iodoaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring iodine and fluorine substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the difluoro and iodo groups can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic cores essential in the manufacture of electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Fluorinated Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments, which offer improved lightfastness and color properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and organofluorine chemistry.

Basic Information

Product Name	3,5-Difluoro-4-Iodoaniline
CAS No.	1542-34-3
Molecular Formula	C6H4F2IN
Molecular Weight	254.99 g/mol
Synonyms	4-Iodo-3,5-difluoroaniline; 3,5-Difluoro-4-iodobenzenamine; 4-Amino-2,6-difluoro-1-iodobenzene; Benzenamine, 3,5-difluoro-4-iodo-; 3,5-Difluoro-4-iodophenylamine; 1542-34-3; 4-Iodo-3,5-difluoro-phenylamine
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Iodoaniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can supply material tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.