Description

4(1H)-Pyrimidinone, 5-Fluoro-2,3-Dihydro-2-Thioxo- (9Ci) is a specialized fluorinated pyrimidinone derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique heterocyclic core enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral, anticancer, and antimicrobial agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme mechanisms and biological pathways.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or ligands for metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential for medicinal chemistry programs and discovery research in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	4(1H)-Pyrimidinone, 5-Fluoro-2,3-Dihydro-2-Thioxo- (9Ci)
CAS No.	1542-23-0
Molecular Formula	C4H3FN2OS
Molecular Weight	146.14 g/mol
Synonyms	5-Fluoro-2,3-dihydro-2-thioxo-4(1H)-pyrimidinone; 5-Fluoro-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 5-Fluoro-2-mercapto-4-hydroxypyrimidine; 5-Fluoro-4-hydroxy-2-mercaptopyrimidine; 5-Fluoro-2-thiouracil; 5-Fluoro-2-thio-4-pyrimidinol; 1542-23-0; 5-Fluoro-2-thioxo-1,2-dihydropyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 4(1H)-Pyrimidinone, 5-Fluoro-2,3-Dihydro-2-Thioxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.