Description

2-(Trifluoromethoxy)Aniline is a versatile fluorinated aromatic amine building block, distinguished by the presence of a trifluoromethoxy substituent on the aniline ring. This unique structure imparts enhanced lipophilicity, metabolic stability, and electronic properties, making it a critical intermediate in advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance pesticidal activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Employed in the production of specialized dyes and pigments, where its structure contributes to color fastness and unique chromatic properties.
• Polymer Modification: Acts as a monomer or additive to introduce fluorine-containing groups into polymers, altering their surface energy, chemical resistance, and optical properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reactions and creating compound libraries for screening.

Basic Information

Product Name	2-(Trifluoromethoxy)Aniline
CAS No.	1535-75-7
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	2-Aminophenyl trifluoromethyl ether; 2-Trifluoromethoxyaniline; o-(Trifluoromethoxy)aniline; 1-Amino-2-(trifluoromethoxy)benzene; 2-(Trifluoromethoxy)benzenamine; Aniline, 2-(trifluoromethoxy)-; α,α,α-Trifluoro-o-anisidine
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Aniline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, acids, and bases. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.