Description

3-(Trifluoromethoxy)Aniline is a versatile aromatic amine building block characterized by a unique trifluoromethoxy substituent. This compound is valued for its ability to impart enhanced lipophilicity, metabolic stability, and electronic properties to target molecules, making it a critical intermediate in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing candidates for central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Intermediate for producing specialized dyes and pigments with unique color fastness and properties.
• Polymer Modification: Used to introduce functional aniline groups into polymer chains, modifying material properties for specialty coatings and resins.
• Research & Development: Essential reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in medicinal and material chemistry.

Basic Information

Product Name	3-(Trifluoromethoxy)Aniline
CAS No.	1535-73-5
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	3-Aminophenyl trifluoromethyl ether; m-(Trifluoromethoxy)aniline; 3-Trifluoromethoxyaniline; 3-(Trifluoromethoxy)benzenamine; α,α,α-Trifluoro-m-anisidine; 1-Amino-3-(trifluoromethoxy)benzene; Aniline, 3-(trifluoromethoxy)-; Benzenamine, 3-(trifluoromethoxy)-
EINECS	216-269-7

Quality Control

Our 3-(Trifluoromethoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.