Description

5-Amino-2-(Trifluoromethyl)Pyrimidine-4,6-Diol is a high-purity, heterocyclic organic compound featuring a pyrimidine core substituted with amino and trifluoromethyl groups, serving as a critical advanced pharmaceutical intermediate. Its molecular structure makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in antiviral, anticancer, and central nervous system (CNS) therapeutic agents.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides, leveraging the biological activity of the pyrimidine scaffold.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for creating complex heterocyclic libraries for high-throughput screening.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials due to its functional groups.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical manufacturing.

Basic Information

Product Name	5-Amino-2-(Trifluoromethyl)Pyrimidine-4,6-Diol
CAS No.	1513-71-9
Molecular Formula	C5H4F3N3O2
Molecular Weight	195.10 g/mol
Synonyms	5-Amino-2-(trifluoromethyl)-4,6-pyrimidinediol; 5-Amino-2-(trifluoromethyl)pyrimidine-4,6(1H,5H)-dione; 5-Amino-2-(trifluoromethyl)uracil; 2-Trifluoromethyl-5-aminouracil; 5-Amino-2-trifluoromethyluracil; 5-Amino-2-(trifluoromethyl)-1H-pyrimidine-4,6-dione; 5-Amino-2-(trifluoromethyl)-4,6-dihydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 5-Amino-2-(Trifluoromethyl)Pyrimidine-4,6-Diol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.