Description

4(3H)-Pyrimidinone, 6-Amino-2-(Trifluoromethyl)- is a high-value trifluoromethylated pyrimidinone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a trifluoromethyl substituent, makes it indispensable for creating novel compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral, anticancer, and anti-inflammatory drug candidates, leveraging the metabolic stability imparted by the trifluoromethyl group.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides where the pyrimidinone core contributes to target specificity and efficacy.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced materials requiring specific electronic or surface properties.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization in medicinal chemistry and process development for scale-up production.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory research and method development in heterocyclic chemistry.

Basic Information

Product Name	4(3H)-Pyrimidinone, 6-Amino-2-(Trifluoromethyl)-
CAS No.	1513-70-8
Molecular Formula	C5H4F3N3O
Molecular Weight	179.10 g/mol
Synonyms	6-Amino-2-(trifluoromethyl)-4(3H)-pyrimidinone; 6-Amino-2-(trifluoromethyl)pyrimidin-4(3H)-one; 2-(Trifluoromethyl)-6-amino-4-pyrimidinol; 6-Amino-2-trifluoromethyl-4-pyrimidinol; 6-Amino-2-trifluoromethyl-4(3H)-pyrimidinone; 6-Amino-2-trifluoromethyl-4-hydroxypyrimidine; 1513-70-8; 4-Pyrimidinol, 6-amino-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4(3H)-Pyrimidinone, 6-Amino-2-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.