Description

2-Amino-4-Hydroxy-6-(Trifluoromethyl)Pyrimidine is a high-value trifluoromethylated pyrimidine derivative, a key heterocyclic building block prized for its ability to impart unique physicochemical properties to target molecules. Its primary commercial value lies in enabling the synthesis of advanced active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries seeking to develop novel therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical scaffold in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used as a key precursor in developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, liquid crystals, and functional polymers.
• Chemical Biology & Proteomics: Employed in designing molecular probes and enzyme inhibitors for biochemical research and drug discovery programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries.

Basic Information

Product Name	2-Amino-4-Hydroxy-6-(Trifluoromethyl)Pyrimidine
CAS No.	1513-69-5
Molecular Formula	C5H4F3N3O
Molecular Weight	179.10 g/mol
Synonyms	6-(Trifluoromethyl)-2,4-pyrimidinediol, 2-Amino-4-hydroxy-6-trifluoromethylpyrimidine; 4-Hydroxy-6-(trifluoromethyl)-2-pyrimidinamine; 2-Amino-6-trifluoromethyl-4-pyrimidinol; 2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine; 4-Pyrimidinol, 2-amino-6-(trifluoromethyl)-; 6-Trifluoromethyl-2,4-dihydroxypyrimidine (tautomer)
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Hydroxy-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF for moisture content, to ensure it meets the stringent requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.