Description

n-Acetyl-D-Methionine is a chemically modified derivative of the essential amino acid D-methionine, specifically the N-acetylated form. This modification enhances its stability and alters its metabolic pathway, making it a valuable chiral building block and intermediate in sophisticated organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors. Its specific stereochemistry is critical for applications requiring high enantiomeric purity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to incorporate protected methionine residues into peptide chains.
• Nutritional Science Studies: Utilized in research models to study the metabolism and utilization of acetylated amino acids.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material for the preparation of enantiomerically pure compounds.
• Reference Standard: Used as a high-purity analytical reference standard in quality control laboratories for HPLC, GC, or MS.

Basic Information

Product Name	n-Acetyl-D-Methionine
CAS No.	1509-92-8
Molecular Formula	C7H13NO3S
Molecular Weight	191.25 g/mol
Synonyms	N-Acetyl-D-methionine; D-2-(Acetylamino)-4-(methylthio)butanoic acid; (R)-2-Acetamido-4-(methylthio)butanoic acid; N-Acetyl-(R)-methionine; Ac-D-Met-OH; N-Acetyl-DL-methionine (isomeric mixture); Acetyl-D-methionine; NSC 3346
EINECS	216-144-6

Quality Control

Our n-Acetyl-D-Methionine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) that include results for assay, chiral purity, and specific impurities. Specifications can meet the requirements for research and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.