Description

D-Alloisoleucine is a non-proteinogenic stereoisomer of the essential branched-chain amino acid isoleucine, distinguished by its specific D-configuration at the alpha carbon. This unique chiral structure makes it a valuable building block in pharmaceutical research, particularly for the synthesis of peptide-based drugs and diagnostic agents where stereochemical purity is critical. It serves as a key chiral intermediate and reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Critical chiral building block for the synthesis of novel peptide therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, metabolic pathway analysis, and microbiological media.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships and to develop peptide hormones or enzyme inhibitors.
• Diagnostic Reagent Manufacturing: Employed in the production of reagents and kits for clinical diagnostics and analytical testing.
• Nutritional Science Studies: Utilized in metabolic research to investigate amino acid metabolism, absorption, and utilization.
• Fine Chemical Synthesis: Serves as a starting material or chiral auxiliary in asymmetric synthesis for high-value specialty chemicals.

Basic Information

Product Name	D-Alloisoleucine
CAS No.	1509-35-9
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	D-α-Amino-β-methylvaleric acid; (2R,3R)-2-Amino-3-methylpentanoic acid; D-Allo-isoleucine; D-iso-Leucine; (R,R)-Isoleucine; D-three-Isoleucine; D-Alloisoleucine; (2R,3R)-Isoleucine
EINECS	216-143-9

Quality Control

Our D-Alloisoleucine is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles. The product meets stringent specifications suitable for research and pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (D-Alloisoleucine)
Optical Rotation [α]	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.