Description

L-Allo-Isoleucine is a non-proteinogenic stereoisomer of the essential branched-chain amino acid isoleucine, distinguished by its unique (2S,3R) configuration. This specific chirality makes it a valuable chiral building block and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers for applications requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard in metabolic pathway studies, enzyme-substrate interaction analysis, and stereochemistry research.
• Nutritional Science Studies: Employed in comparative studies to understand the metabolism and biological effects of different isoleucine stereoisomers.
• Cell Culture Media Component: Can be incorporated into specialized cell culture formulations for specific research applications.
• Standards & Calibration: Essential for calibrating analytical equipment like HPLC and LC-MS in amino acid analysis.
• Peptide Synthesis: Used in the solid-phase or solution-phase synthesis of custom peptides with specific structural features.

Basic Information

Product Name	L-Allo-Isoleucine
CAS No.	1509-34-8
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	(2S,3R)-2-Amino-3-methylpentanoic acid; (2S,3R)-Isoleucine; allo-L-Isoleucine; L-α-Amino-β-methylvaleric acid; (2S,3R)-2-Amino-3-methylvaleric acid; L-(+)-Alloisoleucine; (2S,3R)-3-Methyl-2-aminopentanoic acid
EINECS	216-143-9

Quality Control

Our L-Allo-Isoleucine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical and stereochemical purity, consistent with research-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific rotation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	+38.0° to +42.0° (c=1 in 1N HCl)
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.