Description

L(+)-Homoarginine Hydrochloride is a high-purity, non-proteinogenic amino acid derivative, widely recognized for its role as a biochemical precursor and research tool. Its significance lies in its utility as a specific substrate for nitric oxide synthase (NOS) and as a building block in peptide synthesis, offering researchers and manufacturers a reliable and consistent material. This compound is essential for professionals in pharmaceutical R&D, biochemical research, and fine chemical synthesis, where precise molecular tools are critical for advancing scientific discovery and product development.

Application

• Biochemical Research: Used as a specific substrate in enzymatic studies of nitric oxide synthase (NOS) activity and regulation.
• Pharmaceutical Intermediates: Serves as a key chiral building block in the synthesis of novel peptide-based therapeutics and diagnostic agents.
• Reference Standards: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Nutritional Science Studies: Investigated for its metabolic role and potential applications in specialized nutritional formulations.
• Cell Culture & Microbiology: Utilized in defined media for studying amino acid metabolism in various cell lines and microbial systems.

Basic Information

Product Name	L(+)-Homoarginine Hydrochloride
CAS No.	1483-01-8
Molecular Formula	C7H17N5O2 • HCl
Molecular Weight	239.70 g/mol (Free base: 203.24 g/mol)
Synonyms	L-Homoarginine hydrochloride; (S)-2-Amino-6-(diaminomethylideneamino)hexanoic acid hydrochloride; Homo-L-arginine HCl; NG-(Aminoiminomethyl)-L-lysine hydrochloride; L-2-Amino-6-guanidinohexanoic acid hydrochloride; Agmatine analog; HArg HCl
EINECS	216-048-8

Quality Control

Our L(+)-Homoarginine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity verification, and identity confirmation (IR, NMR), to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition (Sulfated Ash)	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Specific Rotation [α]20/D	+21.0° to +24.0° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.