Description

L-2-Amino-3-Guanidinopropionic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative of significant interest in biochemical research and pharmaceutical development. This compound serves as a crucial building block and a key intermediate for synthesizing more complex peptides and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on metabolic studies, enzyme inhibitors, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of peptide-based drugs and enzyme inhibitors.
• Biochemical Research: Used in metabolic pathway studies and as a substrate or inhibitor in enzymatic assays.
• Peptide Synthesis: Serves as a specialized building block for incorporating the guanidino functional group into custom peptides.
• Reference Standard: Employed as an analytical standard in HPLC and LC-MS for quality control and method development.
• Nutritional Science Research: Investigated for its role in amino acid metabolism and potential bioactive properties.

Basic Information

Product Name	L-2-Amino-3-Guanidinopropionic Acid Hydrochloride
CAS No.	1482-99-1
Molecular Formula	C₄H₁₀N₄O₂ • HCl
Molecular Weight	182.61 g/mol
Synonyms	L-2-Amino-3-guanidinopropanoic Acid Hydrochloride; L-α-Amino-β-guanidinopropionic Acid Hydrochloride; L-Homoarginine Hydrochloride (Note: Homoarginine is a common name for this compound); (S)-2-Amino-3-guanidinopropanoic Acid Hydrochloride; Guanidinoalanine Hydrochloride; β-Guanidino-L-alanine Hydrochloride; NSC 33424; L-AGPA HCl
EINECS	Contact for details

Quality Control

Our L-2-Amino-3-Guanidinopropionic Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for purity (typically by HPLC), chiral purity, residual solvents, and heavy metals is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. After opening, handle under dry conditions and reseal the container immediately.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.