Description

4,6-Pyrimidinediol, 2-(Fluoromethyl)- (6Ci,8Ci) is a fluorinated pyrimidine derivative, a high-value heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a dihydroxypyrimidine core with a reactive fluoromethyl substituent, enabling precise modifications for creating novel compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing new active ingredients, nucleoside analogs, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, including potential antiviral, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and plant growth regulators that require fluorinated heterocyclic structures for enhanced activity and stability.
• Nucleoside & Nucleotide Chemistry: Serves as a crucial precursor in the synthesis of modified nucleosides and nucleotides for biochemical research and therapeutic applications.
• Fine Chemical Building Block: Employed in custom and contract synthesis for constructing complex molecules in material science and specialty chemistry.
• Biochemical Research: Utilized as a standard or probe in enzymatic studies and metabolic pathway investigations due to its structural similarity to natural pyrimidines.

Basic Information

Item	Details
Product Name	4,6-Pyrimidinediol, 2-(Fluoromethyl)- (6Ci,8Ci)
CAS No.	1480-98-4
Molecular Formula	C5H5FN2O2
Molecular Weight	144.10 g/mol
Synonyms	2-(Fluoromethyl)-4,6-pyrimidinediol; 2-(Fluoromethyl)pyrimidine-4,6-diol; 2-Fluoromethyl-4,6-dihydroxypyrimidine; 4,6-Dihydroxy-2-(fluoromethyl)pyrimidine; 2-Fluoromethyluracil; 5-Fluorouracil precursor (related); 1480-98-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of 4,6-Pyrimidinediol, 2-(Fluoromethyl)- is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and high purity. Our standard analytical controls include identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.