Description

5-Fluoro-4-Hydroxy-2-Methyl-Sulfanylpyrimidine is a high-purity pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its unique structure, featuring fluorine and sulfanyl substituents, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of antiviral, anticancer, and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its fluorine-containing pyrimidine core.
• Chemical Research: Serves as a versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies.
• Nucleoside Analog Development: Employed in the synthesis of modified nucleosides and nucleotides for biochemical applications.
• Ligand and Catalyst Preparation: Useful for creating specialized ligands in coordination chemistry and catalysis.

Basic Information

Product Name	5-Fluoro-4-Hydroxy-2-Methyl-Sulfanylpyrimidine
CAS No.	1480-92-8
Molecular Formula	C5H5FN2OS
Molecular Weight	160.17 g/mol
Synonyms	2-(Methylthio)-5-fluoro-4-pyrimidinol; 5-Fluoro-2-methylmercapto-4-pyrimidinol; 5-Fluoro-4-hydroxy-2-(methylthio)pyrimidine; 4-Hydroxy-5-fluoro-2-(methylthio)pyrimidine; 2-Methylsulfanyl-5-fluoro-pyrimidin-4-ol; 5-Fluoro-4-pyrimidinol, 2-(methylthio)-; 5-Fluoro-2-(methylthio)-4(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4-Hydroxy-2-Methyl-Sulfanylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.