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3-o-Methyldopamine Hydrochloride CAS NO 1477-68-5


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CAS No.:1477-68-5

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

3-o-Methyldopamine Hydrochloride is a hydrochloride salt form of a key dopamine metabolite, offering enhanced stability and solubility for research and development applications. This compound is critical for biochemical studies involving catecholamine metabolism, neurological pathways, and receptor activity. It serves as an essential reference standard and synthetic intermediate for pharmaceutical R&D, analytical testing, and academic research in neuroscience and pharmacology.

Application

  • Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quantifying dopamine metabolites in biological samples.
  • Biochemical Research: A vital tool for studying catechol-O-methyltransferase (COMT) enzyme activity and dopamine metabolic pathways in neurological research.
  • Neuroscience Studies: Employed in receptor binding assays and as a precursor in synthesizing compounds for investigating Parkinson's disease and other neurological disorders.
  • Metabolite Analysis: Essential for clinical and preclinical studies to understand the pharmacokinetics and pharmacodynamics of dopaminergic drugs.
  • Organic Synthesis: Serves as a protected synthetic building block for the preparation of more complex molecules targeting the central nervous system.

Basic Information

Product Name 3-o-Methyldopamine Hydrochloride
CAS No. 1477-68-5
Molecular Formula C9H14ClNO2
Molecular Weight 203.66 g/mol
Synonyms 3-Methoxytyramine Hydrochloride; 4-(2-Aminoethyl)-2-methoxyphenol Hydrochloride; 3-O-Methyl Dopamine HCl; 3-OMe-DA HCl; 3-Methoxy-4-hydroxyphenethylamine Hydrochloride; 3-MT HCl; DL-3-Methoxytyramine Hydrochloride
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Quality Control

Our 3-o-Methyldopamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling. Certificates of Analysis (COA) detailing purity, chromatographic data, and residual solvent levels are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥98.0%
Water Content (KF) ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm
Related Substances (HPLC) Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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