Description

2-Mercaptopyrimidine is a versatile heterocyclic building block and a key intermediate in organic synthesis, valued for its reactive thiol and pyrimidine functionalities. Its primary commercial importance lies in its role as a precursor for the synthesis of pharmaceuticals, agrochemicals, and advanced materials. This compound is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the pyrimidine core is a key structural motif.
• Ligand and Catalyst Preparation: Serves as a precursor for creating metal-chelating ligands used in catalysis and material science.
• Nucleic Acid Research: Employed in biochemical research as a modified nucleobase analog for studying nucleic acid structure and function.
• Fine Chemical Synthesis: A versatile reagent for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Material Science: Used in the development of organic electronic materials and polymers due to its electron-rich aromatic system.

Basic Information

Product Name	2-Mercaptopyrimidine
CAS No.	1450-85-7
Molecular Formula	C4H4N2S
Molecular Weight	112.15 g/mol
Synonyms	2-Pyrimidinethiol; Pyrimidine-2-thiol; 2-Thiopyrimidone; 2-Mercaptopyrimidine; 2-Pyrimidinol, thioxo-; 2(1H)-Pyrimidinethione; 2-Sulfanylpyrimidine; 2-Thioxo-1,2-dihydropyrimidine; NSC 403697
EINECS	215-909-4

Quality Control

Our 2-Mercaptopyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	198°C - 202°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.