Description

5-Bromo-4-tert-Butylpyrimidine is a high-purity, halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine atom and a bulky tert-butyl group, makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Ligand & Catalyst Development: Serves as a sophisticated ligand precursor in transition metal catalysis for cross-coupling and other C-H functionalization reactions.
• Material Science Research: Employed in the creation of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Scale-Up: A fundamental starting material for contract research organizations (CROs) and CDMOs performing custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	5-Bromo-4-tert-Butylpyrimidine
CAS No.	1439-08-3
Molecular Formula	C8H11BrN2
Molecular Weight	215.09 g/mol
Synonyms	4-tert-Butyl-5-bromopyrimidine; 5-Bromo-4-(1,1-dimethylethyl)pyrimidine; 5-Bromo-4-(tert-butyl)pyrimidine; 5-Bromo-4-tert-butyl-pyrimidine; Pyrimidine, 5-bromo-4-(1,1-dimethylethyl)-; 1439-08-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-tert-Butylpyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceable quality supports your regulatory and process development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.