Description

1,3-Dichloro-4-Fluorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization, making it a critical intermediate for creating complex molecules. This compound is primarily needed by R&D laboratories and production facilities in the pharmaceutical and agrochemical sectors for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, or other physical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the dichlorofluorophenyl moiety into more complex structures.
• Dyestuff & Pigment Intermediate: Used in the production of specialized dyes and pigments requiring halogenated aromatic cores.

Basic Information

Product Name	1,3-Dichloro-4-Fluorobenzene
CAS No.	1435-48-9
Molecular Formula	C6H3Cl2F
Molecular Weight	164.99 g/mol
Synonyms	4-Fluoro-1,3-dichlorobenzene; 1,3-Dichloro-4-fluorobenzene; 2,4-Dichlorofluorobenzene; 4-Fluororesorcinol Dichloride; 3,5-Dichloro-4-fluorobenzene (incorrect but common misnomer); FDCB; Benzene, 1,3-dichloro-4-fluoro-
EINECS	215-859-8

Quality Control

Our 1,3-Dichloro-4-Fluorobenzene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.50 g/cm³
Boiling Point	~185-190 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.