Description

Acth Alpha (1-18) is a synthetic peptide fragment corresponding to the first eighteen amino acids of the Adrenocorticotropic Hormone (ACTH). This compound is a critical research tool for studying the structure-activity relationships of ACTH and its role in stimulating corticosteroid production. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on endocrinology, peptide chemistry, and therapeutic development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the physiological functions and metabolic pathways of ACTH.
• Pharmaceutical Development: Serves as a key intermediate or model compound in the research and development of peptide-based therapeutics targeting adrenal function.
• Endocrinology Studies: Essential for in vitro and in vivo assays to understand corticosteroid synthesis regulation and related disorders.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry for method development, calibration, and quality control of related peptide products.
• Biochemical Reagent: Functions as a specific ligand in receptor binding studies and signal transduction research within the hypothalamic-pituitary-adrenal axis.

Basic Information

Product Name	Acth Alpha (1-18)
CAS No.	1285-85-4
Molecular Formula	C₁₀₀H₁₅₀N₂₈O₃₁S
Molecular Weight	2283.6 g/mol
Synonyms	ACTH (1-18); Adrenocorticotropic Hormone (1-18); Corticotropin (1-18); α-MSH/ACTH (1-18); Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-OH; ACTH Fragment 1-18
EINECS	Contact for details

Quality Control

Our Acth Alpha (1-18) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide Certificates of Analysis (COA) with detailed results for traceability and compliance. Specifications are aligned with research-grade standards, ensuring consistency and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.