Description

Thiocholesterol is a sulfur-containing derivative of cholesterol, a key intermediate in the synthesis of various bioactive compounds. This organosulfur compound is valued for its role in modifying the properties of steroidal frameworks, enabling the development of novel materials and pharmaceuticals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, life science, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroidal drugs and therapeutic agents.
• Biochemical Research: Used in the study of membrane biology, lipid rafts, and as a precursor for labeled cholesterol analogs.
• Liquid Crystal Materials: Serves as a chiral dopant or component in the development of advanced liquid crystal displays (LCDs).
• Liposome & Drug Delivery Systems: Incorporated into lipid formulations to enhance stability or modify the release profile of encapsulated drugs.
• Chemical Synthesis: Acts as a versatile intermediate for introducing thioether or other sulfur-based functional groups into complex molecules.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Thiocholesterol
CAS No.	1249-81-6
Molecular Formula	C27H46S
Molecular Weight	402.73 g/mol
Synonyms	5-Cholestene-3β-thiol; 3β-Thiocholesterol; 3-Thiocholesterol; 3β-Mercaptocholest-5-ene; Cholest-5-ene-3β-thiol; 3β-Hydroxycholest-5-ene Thioether (deprotonated form); Thiocholesterol (common name)
EINECS	215-008-4

Quality Control

Our Thiocholesterol is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure high purity and consistency, meeting the rigorous standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.