Description

Dansyl-L-Proline is a high-purity, fluorescently labeled derivative of the amino acid L-proline, widely recognized under the CAS registry number 1239-94-7. This compound is a critical reagent in advanced biochemical research and analytical method development due to its excellent fluorescence properties. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications requiring sensitive detection and quantification.

Application

• Fluorescent Labeling Agent: Used for the derivatization of amino acids, peptides, and other compounds to enhance their detectability in chromatographic analyses like HPLC.
• Biochemical Research: Serves as a probe or tracer in enzyme studies, receptor binding assays, and metabolic pathway investigations.
• Pharmaceutical Analysis: Employed in the development and validation of analytical methods for the quantification of proline and related compounds in drug substances and products.
• Proteomics and Peptide Chemistry: Acts as a modifying agent for N-terminal or specific residue labeling in peptides for purification, detection, or structural studies.
• Diagnostic Reagent Development: A potential component in developing fluorescent assays or kits for clinical diagnostics and biomedical testing.
• Quality Control Standard: Used as a certified reference material or internal standard in analytical laboratories to ensure method accuracy and precision.

Basic Information

Product Name	Dansyl-L-Proline
CAS No.	1239-94-7
Molecular Formula	C₁₇H₂₀N₂O₄S
Molecular Weight	348.42 g/mol
Synonyms	1-(5-Dimethylaminonaphthalene-1-sulfonyl)-L-proline; L-Proline, 1-[(5-dimethylamino-1-naphthalenyl)sulfonyl]-; DNS-Proline; Dansylproline; N-Dansyl-L-proline; Proline Dansyl Derivative; 5-Dimethylaminonaphthalene-1-sulfonyl-L-proline
EINECS	214-983-6

Quality Control

Our Dansyl-L-Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification, and loss on drying, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.