Description

n-ε-Benzoyl-L-Lysine CAS NO 1219-46-1 is a protected derivative of the essential amino acid L-lysine, where the ε-amino group is specifically blocked by a benzoyl group. This modification is critical for enabling selective peptide synthesis and biochemical research, preventing unwanted side reactions at the lysine side chain. It serves as a vital building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, well-defined intermediates for advanced applications.

Application

• Peptide Synthesis Intermediate: A key protected amino acid for the solid-phase and solution-phase synthesis of complex peptides and proteins.
• Biochemical Research: Used in enzymatic studies and as a substrate or inhibitor in research involving lysine-specific enzymes.
• Pharmaceutical Development: Serves as a precursor in the development of novel therapeutic agents, including enzyme inhibitors and targeted drug conjugates.
• Proteomics & Bioconjugation: Facilitates site-specific labeling and modification of proteins for analytical and diagnostic purposes.
• Fine Chemical Production: Employed in the custom synthesis of specialized organic compounds for various industrial applications.

Basic Information

Product Name	n-ε-Benzoyl-L-Lysine
CAS No.	1219-46-1
Molecular Formula	C13H18N2O3
Molecular Weight	250.29 g/mol
Synonyms	N6-Benzoyl-L-lysine; Nε-Benzoyl-L-lysine; Bz-Lys-OH; (S)-2-Amino-6-benzamidohexanoic acid; L-Lysine, N6-benzoyl-; Benzoyllysine; N-α-Benzoyl-L-lysine (Note: This is a common misnomer, the correct site is epsilon); N-Bzl-Lys
EINECS	214-950-7

Quality Control

Our n-ε-Benzoyl-L-Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	+18.0° to +22.0° (c=1 in 1N HCl)
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.