Description

n-Acetyl-L-Tryptophan is a chemically modified derivative of the essential amino acid L-tryptophan, widely recognized for its enhanced stability and specific biological activity. This compound is a critical intermediate in pharmaceutical synthesis and a valuable research tool in biochemical studies. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and life science research sectors for developing therapeutic agents and advanced biochemical assays.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Nutraceutical Formulation: Incorporated into advanced dietary supplements targeting neurological health and sleep regulation due to its precursor role in serotonin synthesis.
• Cell Culture Media: Serves as a specialized nutrient component in defined media for mammalian cell culture and bioprocessing.
• Cosmetic Actives: Employed in the development of high-end skincare products for its potential antioxidant and skin-conditioning properties.
• Reference Standard: Provides a high-purity standard for quality control and analytical method development in pharmaceutical and food testing laboratories.

Basic Information

Product Name	n-Acetyl-L-Tryptophan
CAS No.	1218-34-4
Molecular Formula	C13H14N2O3
Molecular Weight	246.26 g/mol
Synonyms	N-Acetyl-L-tryptophan; N-Acetyltryptophan; L-Tryptophan, N-acetyl-; Acetyl-L-tryptophan; (S)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid; 1H-Indole-3-propanoic acid, α-acetamido-, (αS)-; AT; N-Ac-Trp-OH; NSC 8216
EINECS	214-943-1

Quality Control

Our n-Acetyl-L-Tryptophan is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-30.0° to -34.0° (c=1 in H2O)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.