Description

Ac-Trp-Oh CAS NO 1218-34-3 is a high-purity, protected amino acid derivative, specifically N-Acetyl-L-tryptophan. This compound serves as a critical building block and intermediate in advanced organic synthesis and peptide research. It is essential for pharmaceutical R&D, particularly in the development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex peptides and bioconjugates with therapeutic potential.
• Biochemical Research: Used in proteomics and enzymology studies as a substrate or a modified amino acid residue to investigate protein structure and function.
• Peptide Synthesis: An essential protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS) for creating custom peptide sequences.
• API Development: Intermediate in the research and scale-up production of new Active Pharmaceutical Ingredients, especially those targeting neurological and metabolic pathways.
• Reference Standard: Serves as a chromatographic reference standard in analytical laboratories for quality control and method development.
• Cosmetic Peptides: Potential intermediate for synthesizing bioactive peptides used in advanced skincare and cosmetic formulations.

Basic Information

Product Name	Ac-Trp-Oh
CAS No.	1218-34-3
Molecular Formula	C13H14N2O3
Molecular Weight	246.26 g/mol
Synonyms	N-Acetyl-L-tryptophan; Ac-L-Trp-OH; (S)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid; N-Acetyltryptophan; N-Acetyl-L-tryptophane; Acetyl-L-tryptophan; L-N-Acetyltryptophan; N-Acetyl-L-α-tryptophan
EINECS	214-945-8

Quality Control

Our Ac-Trp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	-30.0° to -34.0° (c=1 in 1N HCl)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.