Description

5-Bromodihydro-24(1H3H)-Pyrimidinedione is a specialized brominated heterocyclic compound that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique pyrimidinedione core functionalized with a bromine atom makes it a versatile building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to the reactive bromine substituent.
• Material Science Research: Investigated as a monomer or precursor for creating specialized polymers and organic electronic materials.
• Academic & R&D Laboratories: Serves as a standard or starting material for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	5-Bromodihydro-24(1H3H)-Pyrimidinedione
CAS No.	1193-76-6
Molecular Formula	C4H3BrN2O2
Molecular Weight	190.98 g/mol
Synonyms	5-Bromo-2,4(1H,3H)-pyrimidinedione; 5-Bromouracil; 5-BU; 5-Bromo-1H-pyrimidine-2,4-dione; 5-Bromo-2,4-dihydroxypyrimidine; 5-Bromopyrimidine-2,4(1H,3H)-dione; NSC 38297
EINECS	214-771-7

Quality Control

Our 5-Bromodihydro-24(1H3H)-Pyrimidinedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	293-298 °C (dec.)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.