Description

5-Chloro-6-Hydroxy-1H-Pyrimidin-4-One is a versatile heterocyclic building block and key intermediate in organic synthesis. This compound matters for its role as a critical precursor in the development of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical producers for creating novel compounds and scaling up production processes.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs and other antiviral or anticancer drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its pyrimidine core structure.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds in research and development.
• Biochemical Research: Employed in studies involving enzyme inhibitors and as a modifier in nucleotide chemistry.
• Material Science: Potential precursor for the synthesis of specialty polymers and ligands for metal coordination complexes.

Basic Information

Product Name	5-Chloro-6-Hydroxy-1H-Pyrimidin-4-One
CAS No.	1193-56-2
Molecular Formula	C4H3ClN2O2
Molecular Weight	146.53 g/mol
Synonyms	5-Chloro-6-hydroxypyrimidin-4(1H)-one; 4(1H)-Pyrimidinone, 5-chloro-6-hydroxy-; 5-Chloro-6-hydroxy-4-pyrimidinol; 5-Chloro-4,6-dihydroxypyrimidine; 5-Chlorouracil (common name); 6-Hydroxy-5-chloropyrimidin-4(1H)-one; NSC 403697
EINECS	214-777-9

Quality Control

Our 5-Chloro-6-Hydroxy-1H-Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.