Description

Mevalonate is a critical intermediate in the mevalonate pathway, the essential biosynthetic route for isoprenoids and sterols. This high-purity compound is vital for research and development in metabolic studies and as a precursor in fine chemical synthesis. It is primarily utilized by the pharmaceutical, biotechnology, and life science research industries for applications ranging from enzyme assays to the development of novel therapeutics.

Application

• Biochemical Research: Essential substrate for studying the activity of enzymes in the mevalonate pathway, such as HMG-CoA reductase.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of sterols, isoprenoids, and other bioactive molecules.
• Metabolite Analysis: Used as a standard in analytical methods (LC-MS, GC-MS) for quantifying metabolic flux in cellular systems.
• Nutraceutical Development: Investigated for its role in the production of coenzyme Q10 and other supplements.
• Enzyme Inhibition Studies: Employed in screening and characterizing potential inhibitors targeting cholesterol biosynthesis.
• Microbial Fermentation: Acts as a precursor in engineered microbial strains for the production of high-value terpenoids.

Basic Information

Product Name	Mevalonate
CAS No.	1192-42-3
Molecular Formula	C6H12O5
Molecular Weight	164.16 g/mol
Synonyms	(R)-Mevalonic acid; (R)-Mevalonate; 3,5-Dihydroxy-3-methylpentanoic acid; 3-Methyl-3,5-dihydroxypentanoic acid; Mevalonic acid; D-Mevalonic acid; (R)-3,5-Dihydroxy-3-methylvaleric acid
EINECS	214-765-6

Quality Control

Our Mevalonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC or titration assay results, confirming identity, purity, and the absence of critical impurities. Our quality commitment aligns with standards suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Loss on Drying	≤ 2.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.