Description

n-Carbamyl-L-Glutamic Acid is a key biochemical intermediate and a stable analog of N-acetylglutamate, an essential allosteric activator of carbamoyl phosphate synthetase I. This compound is of significant value in metabolic research and pharmaceutical development due to its role in the urea cycle and arginine biosynthesis. It is primarily required by researchers and manufacturers in the life sciences, pharmaceutical, and nutraceutical industries for applications ranging from enzyme studies to potential therapeutic formulations.

Application

• Biochemical Research: Used as a stable research tool to study the urea cycle, nitrogen metabolism, and the function of carbamoyl phosphate synthetase.
• Pharmaceutical Intermediates: Serves as a critical building block or precursor in the synthesis of more complex pharmaceutical compounds.
• Diagnostic Reagents: Employed in the formulation of diagnostic kits and assays for metabolic disorder testing.
• Enzyme Activity Studies: Acts as an activator or substrate analog in enzymatic assays to investigate kinetics and inhibition.
• Nutritional Science: Investigated for its potential role in amino acid metabolism and related nutritional supplements.
• Reference Standards: Used as a high-purity certified reference material (CRM) for quality control and analytical method development.

Basic Information

Product Name	n-Carbamyl-L-Glutamic Acid
CAS No.	1188-38-1
Molecular Formula	C6H10N2O5
Molecular Weight	190.15 g/mol
Synonyms	N-Carbamoyl-L-glutamic acid; L-N-Carbamylglutamic acid; Carbamylglutamic acid; Carglumic acid (USAN); N-Carbamylglutamate; (2S)-2-(Carbamoylamino)pentanedioic acid; N-Carbamoylglutamate; L-Carbamylglutamic acid
EINECS	214-710-3

Quality Control

Our n-Carbamyl-L-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	+15.0° to +18.0° (c=1 in 1N HCl)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.