Description

o-Aminoserine is a non-proteinogenic amino acid derivative featuring an amino group on the ortho position of the serine side chain. This unique structure makes it a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and industrial manufacturers in the life sciences sector for developing novel compounds, including peptide mimetics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the synthesis of modified peptides and peptide mimetics to alter biological activity or stability.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzymatic research.
• Asymmetric Synthesis: Employed as a building block for constructing complex molecules with specific stereochemistry in medicinal chemistry.
• Ligand and Chelator Synthesis: Useful for creating specialized ligands for metal catalysis or diagnostic imaging agents.

Basic Information

Product Name	o-Aminoserine
CAS No.	1187-83-3
Molecular Formula	C3H8N2O3
Molecular Weight	120.11 g/mol
Synonyms	2-Amino-3-hydroxypropanoic acid; 3-Hydroxy-2-aminopropionic acid; 2-Aminoserine; (R,S)-2-Amino-3-hydroxypropanoic acid; DL-2-Aminoserine; (±)-2-Aminoserine; 2-Amino-3-hydroxypropionic acid; α-Amino-β-hydroxypropionic acid
EINECS	214-695-6

Quality Control

Our o-Aminoserine is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, chiral purity, and residual solvent analysis, in line with industry best practices. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.