Description

7-Azatryptophan Monohydrate is a high-purity, non-proteinogenic amino acid analog of tryptophan, where a nitrogen atom replaces the carbon at the 7-position of the indole ring. This structural modification makes it a valuable biochemical tool and a critical building block in advanced research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of medicinal chemistry, proteomics, and advanced material science who require precise, high-quality intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological pathways or acting as enzyme inhibitors.
• Biochemical Research: Used as a stable isotopic label or a fluorescent probe analog in metabolic pathway studies and protein interaction analysis.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships (SAR) and to create peptides with modified biological properties.
• Enzyme Substrate Studies: Acts as a substrate or inhibitor analog for enzymes like tryptophan synthase or decarboxylase, aiding in mechanistic studies.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC or LC-MS methods.
• Material Science: Investigated for the development of specialized organic compounds and advanced polymeric materials.

Basic Information

Product Name	7-Azatryptophan Monohydrate
CAS No.	1137-00-4
Molecular Formula	C11H11N3O2 • H2O
Molecular Weight	235.24 g/mol
Synonyms	7-Azatryptophan Hydrate; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 1-(aminomethyl)-, monohydrate; 1-(Aminomethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid monohydrate; 7-Aza-DL-tryptophan monohydrate; 7-Azatryptophan hydrate; Azatryptophan monohydrate
EINECS	Contact for details

Quality Control

Every batch of our 7-Azatryptophan Monohydrate is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive testing includes identity confirmation, purity assay, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	6.0% - 8.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.